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Cells were selected for growth on plates in the presence of estradiol or the antiestrogen TOT. Suggest that neuronal cell death may contribute to some of the CNS symptoms observed with long-term use of AAS. If used during pregnancy, isotretinoin can cause serious birth defects. Treatment for steroid abuse may include meetings with a psychologist, Dure Pharma Test-E endocrine therapies to restore normal hormone levels, and other pharmacological treatments.
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